About Us

The Awadalla Lab, headed by Philip Awadalla, is jointly housed at the Ontario Institute for Cancer Research and the University of Toronto. Working with genomic data, and through the development of computational tools, the laboratory interrogates genomic and environmental contributions associated with the frequency and severity of diseases in human populations.

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Featured Research

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Gene-by-environment interactions in urban populations modulate risk phenotypes.
Marie-Julie Favé, Fabien C. Lamaze, David Soave, Alan Hodgkinson, Héloise Gauvin, Vanessa Bruat, Jean-Christophe Grenier, Elias Gbeha, Kimberly Skead, Audrey Smargiassi, Markey Johnson, Youssef Idaghdour, Philip Awadalla
Nature Communications. 2018. doi: 10.1038/s41467-018-03202-2

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The impact of recombination on human mutation load and disease.
Isabel Alves, Armande Ang Houle, Julie G Hussin, Philip Awadalla
The Royal Society. 2017. 372(1736). doi: 10.1098/rstb.2016.0465

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Recombination affects accumulation of damaging and disease-associated mutations in human populations.
Hussin JG, Hodgkinson A, Idaghdour Y, Grenier JC, Goulet JP, Gbeha E, Hip-Ki E, Awadalla P
Nature genetics. 2015. 47(4). doi: 10.1038/ng.3216

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